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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
6.06
Human Site:
S217
Identified Species:
8.33
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S217
I
S
N
T
S
T
Q
S
L
T
A
E
T
K
D
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S217
I
S
N
T
S
T
Q
S
L
T
A
E
T
K
D
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
L217
S
N
M
S
T
Q
S
L
T
A
E
T
K
D
M
Dog
Lupus familis
XP_533766
1089
122761
E217
I
S
N
M
S
M
A
E
T
K
D
M
V
L
E
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
E217
S
T
Q
S
L
T
A
E
T
K
D
M
A
L
E
Rat
Rattus norvegicus
NP_446123
1093
121882
T217
T
S
T
Q
S
L
T
T
E
T
K
D
M
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
L217
K
S
S
G
K
R
G
L
G
S
P
T
E
S
L
Chicken
Gallus gallus
O42184
1433
161009
V221
E
L
K
I
G
D
R
V
L
V
G
G
T
K
A
Frog
Xenopus laevis
Q5PQ23
649
75475
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
P217
D
V
P
L
T
N
V
P
S
S
S
S
E
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
D169
T
S
D
N
A
E
G
D
G
E
D
D
D
D
E
Honey Bee
Apis mellifera
XP_394037
1326
150590
R244
S
P
V
S
T
S
N
R
L
S
F
V
S
P
E
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
G799
K
L
A
T
I
L
T
G
F
Q
S
Q
I
R
W
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
V217
D
V
G
L
P
E
P
V
L
P
Q
G
T
A
L
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
D212
H
N
V
S
H
T
P
D
S
T
D
E
Q
E
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
Q193
S
Q
D
S
Q
P
E
Q
P
K
S
E
A
E
E
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
0
26.6
N.A.
6.6
20
N.A.
6.6
20
0
0
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
100
20
33.3
N.A.
26.6
33.3
N.A.
20
26.6
0
26.6
N.A.
33.3
46.6
26.6
13.3
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
40
N.A.
N.A.
46.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
6
0
12
0
0
6
12
0
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
0
0
6
0
12
0
0
24
12
6
12
12
% D
% Glu:
6
0
0
0
0
12
6
12
6
6
6
24
12
12
36
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
6
0
0
0
0
% F
% Gly:
0
0
6
6
6
0
12
6
12
0
6
12
0
6
0
% G
% His:
6
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
18
0
0
6
6
0
0
0
0
0
0
0
6
0
0
% I
% Lys:
12
0
6
0
6
0
0
0
0
18
6
0
6
18
0
% K
% Leu:
0
12
0
12
6
12
0
12
30
0
0
0
0
12
18
% L
% Met:
0
0
6
6
0
6
0
0
0
0
0
12
6
0
6
% M
% Asn:
0
12
18
6
0
6
6
0
0
0
0
0
0
0
0
% N
% Pro:
0
6
6
0
6
6
12
6
6
6
6
0
0
6
0
% P
% Gln:
0
6
6
6
6
6
12
6
0
6
6
6
6
0
0
% Q
% Arg:
0
0
0
0
0
6
6
6
0
0
0
0
0
6
0
% R
% Ser:
24
36
6
30
24
6
6
12
12
18
18
6
6
6
0
% S
% Thr:
12
6
6
18
18
24
12
6
18
24
0
12
24
0
0
% T
% Val:
0
12
12
0
0
0
6
12
0
6
0
6
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _